Accurate evaluation of risk factors for mortality may improve early appropriate therapeutic management. American and European experts have recommended empirical antifungal therapy in high-risk patients in the ICU. Identifying this subset of patients thus appears very relevant. Clinical prediction scores have emerged but their poor positive predictive values could lead to overtreatment with antifungals. Bruyere et Al elaborated a plan, where antifungals were given only to patients with a high risk of IC (CS≥3 points) and uncontrolled sepsis despite well-conducted antibiotic therapy for at least 2 days. This strategy could be implemented by the use of a dedicated app, to test its efficacy in large clinical settings.
История обновлений
1.0
2016-10-22
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