2.5.3
2023-04-12
- Now initial target (Start and maintenance) can be set after real-time is on
- Minor bugs fixed
2.5.2
2023-03-06
- Fixed a bug when opening files
- New PK model for Dexmedetomidine in neonates: Zuppa BJA model 2019:123(6):839
- Improved TCI algorithm
2.5.1
2023-02-19
- New PK model for Dexmedetomidine in neonates: Zappa model BJA 2019: 123(6):839
- TCI algorithm improved
2.5
2022-10-04
- Improved TCI algorithm for better accuracy with fewer infusion changes.
-Now you can modify the accuracy of the algorithm between 99% or 95%, to calculate a simpler scheme but with lower accuracy. Tap the "More" button to modify the accuracy
- New option for induction calculation, go to settings and enable "Bolus/Infusion without delay" to calculate an initial scheme with a bolus and an infusion starting at the same time
2.4.1
2022-09-17
- Create templates to build generic schemes, to more quickly set up your induction scheme, to then perform a fine titration using iTIVA
- Morse general model for Dexmedetomidine added (for kids and Adults)
- Do a long tap in the scheme list to COPY/PASTE any infusion scheme, you can choose to copy in ML/hr or according the patient weight
- Share your case through Whatsapp or Airdrop in 2 taps, Tap "MORE" button and then "SHARE"
2.4
2022-07-26
- PK/PD graph now can be set in full screen double tapping
- Added 6 pharmacodynamics models to explore interaction between opioids and propofol / Sevoflurane
- Added PD BIS prediction for propofol Eleveld's model
- Increase simulation speed up to 30 times, ideal for teaching and workshops
- Added real-time decrement time calculation: Swipe to the right in the horizontal bars
- Added Scott PK model for Alfentanil
2.3
2022-06-19
- Remimazolam added
- Etomidate added
- ICU PK models for Midazolam added
- Minor issues fixed
2.02
2021-12-07
- New feature: set a custom Ke0, using the "TIME TO PEAK" method, so now you can modify the pharmacodynamics of any model.
The "time to peak" is the time from the first bolus to the maximum effect measured (using any method, clinical, EEG, BIS, entropy, etc.).
To SET a new "TIME TO PEAK", add a new anesthetic drug, tap the "More" button (in the lower right corner) and then "TIME TO PEAK".
- New feature: Pre-alerts, iTIVA will generate a warning sound before any infusion change, to modify this option open the menu -> Configuration
2.01
2021-10-07
- Fixed some text size issues in the lateral menu after last update
- Added a FILE MANAGER: NOW you can save your simulation cases to review them later, share with colleagues (e-mail, WhatsApp or AirDrop) or run multiple simulations at time.
- Set the end time of your simulation cases and save them for later analysis. (Press the MORE button -> END CASE)
- Select custom alert tones for iTIVA notifications: You can pick over 40 different tones. (Go to Setting-> Tones)
- Added a new ketamine model: Klamp
- Eleveld-h model renamed to Eleveld 1.0
- Obese adjustments mode deleted, now models are filter according the best evidence
- Minto model for remifentanil now can be selected using James equation (original) or Janmahastian (For obese pts) to calculated the lean body mass
- Shafer model for fentanyl now have 3 options, without covariables, real weight and adjusted weight for obeses patients over 80 kg
- Minor bugs fixed
2.0
2021-10-01
- Added a file manager: Now you can save your simulation cases to review them later, share with colleagues (e-mail, WhatsApp or AirDrop) or run multiple simulations at time.
- Set the end time of your simulation cases and save them for later analysis. (Press the MORE button -> END CASE)
- Select custom alert tones for iTIVA notifications: You can pick over 40 different tones. (Go to Setting-> Tones)
- Added a new ketamine model: Klamp
- Eleveld-h model renamed to Eleveld 1.0
- Obese adjustments mode deleted, now models are filter according the best evidence
- Minto model for remifentanil now can be selected using James equation (original) or Janmahastian (For obese pts) to calculated the lean body mass
- Shafer model for fentanyl now have 3 options, without covariables, real weight and adjusted weight for obeses patients over 80 kg
- Minor bugs fixed
1.86.1
2021-04-06
- Fixed a bug added in the last update that impeded the correct data transfer using QR codes
- Fixed some errors in the rocuronium PK models - Thanks to Dr. Eleveld
- Enter individual Cr clearances or serum Cr when using Kleijn's model for rocuronium
- Now you can switch between bolus or infusion mode, just double-tap over the horizontals bars
- Fixed some screen size mismatch issues with some iPhone models
1.86
2021-04-03
- Fixed some errors in the rocuronium PK models - Thanks to Dr. Eleveld
- Enter individual Cr clearances or serum Cr when using Kleijn's model for rocuronium
- Now you can switch between bolus or infusion mode, just double-tap over the horizontals bars
- Fixed some screen size mismatch issues with some iPhone models
- Minor bugs fixed
1.85
2020-11-15
- Minor bugs fixed that should decrease random crashes.
- Fixed some bugs that crashed the App when using mixed drugs
- Now drugs can be synchronized while in real-time mode.
- New option for synchronizing drugs: now you can choose if want to include the boluses while synchronizing, so boluses doses can keep independent while infusion keeps sync.
- Cr clearance calculation added to the first aid library
- Minor improvements in the PK/PD graph
1.84
2020-11-10
- Improved TCI algorithm:
- Fewer modifications to achieve a new target with a 98% precision
- Low target precision improved
- Minor bug fixes
1.83
2020-11-01
- Fixed minor bugs in PK / PD chart
- Small improvements in the interface
1.82
2020-09-07
- Added 4 new rocuronium PK models
- TOF prediction for rocuronium
- New ketamine PK models were added in children under 1 year
- New video tutorial in English
- Minor fixes
1.81
2020-07-28
- Minor bugs fixed
- Rocuronium Kleijn model now show TOF value for a given effect site concentration
1.8
2020-04-09
- Two Heparin PK models for CPB added / Residual heparin calculation
- Protamine PK model added with interaction with Heparin PK model
- Rocuronium Kleijn PK model now can be graduated by renal function
1.7
2019-12-18
- Diazepam added
- New Alfentanil PK model for kids: Goresky
- New PK model for vecuronium
- Small tutorial added
- Solved conflict when the TCI target is set to zero
- Scheme list improved, now volume less than 10 ml is shown with decimal precision
- First aid section with an improved search bar
- Splash screen added
- Minor bugs corrected
1.6.2
2019-10-16
- Compatibility issues with iOS 13 fixed
- Fixed: background music stops when an iTIVA alerts about a new infusion change
1.6.1
2019-09-19
- First aids section updated and a search bar added
- Minor bugs corrected
1.6
2019-09-17
- Simulate up to 6 drugs at time
- Magnesium sulfate added
- Now you can modify the patient weight for a specific drug
- Improved TCI algorithm
- Bugs fixed
1.5.1
2019-09-04
- New drug: Atracurium with 2 PK models for pediatrics and adults
- TCI algorithm improved for neuromuscular blockers
- Minor bugs corrected
1.5
2019-09-01
- Minor bugs corrected
- TCI algorithm improved
1.4
2019-05-10
- Improved App speed
- The time Axis in the GRAPH can be changed to real time format "HH:mm" - Open "side menu" -> Setting -> Enable: Time axis HH:mm
- Historical targets modifications during simulation now can be plotted in the GRAPH, Open the graph, press ""MORE" button -> "SHOW TARGETS"
- Events now can be added to the GRAPH, Open the graph, press ""MORE" button -> "SHOW EVENTS"
- To add events, just press in an empty channel, and look for "Events" in the same list you find all available medications
- Tap over the concentration indicator in each channel, to change between Effect to Plasma concentration, and vice versa
- Minor bugs fixed