AnestAssist PK/PD Hack 1.9 + Redeem Codes
Developer: Palma Healthcare Systems LLC
Category: Medical
Price: $4.99 (Download for free)
Version: 1.9
ID: com.palmahealthcare.AnestAssistStandard
Screenshots
Description
AnestAssist PK/PD is an educational tool used for understanding and visualizing the pharmacokinetics, pharmacodynamics, and interactions of commonly used anesthetic drugs.
Anesthesiologists, CRNA’s, veterinarians, and other clinicians involved with anesthesiology, from residents to the very experienced, will find AnestAssist a valuable tool for understanding rational dosing strategies tailored to individual patients.
Mathematical models, published in peer reviewed anesthesia journals (see www.palmamhealthcare.com), which take into account patient weight, age, and gender, are used to estimate and chart:
Plasma Concentration (IV drugs)
Alveolar Concentration (Inhaled agents)
Effect Site Concentration
Probability of Effect (individual and combined drug interactions)
Analgesia: No response to laryngoscopy
Sedation: OAA/S < 2
NMB: T1/T0=50%
IV drugs included: Propofol, Remifentanil, Fentanyl, Alfentanil, Sufentanil, Dexmedetomidine, Ketamine, Lidocaine, Morphine, Midazolam, Atracurium, Cisatracurium, Rocuronium, and Vecuronium.
Inhaled agents included: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, and Nitrous Oxide.
Interactions modeled: Propofol, Sevoflurane, or Isoflurane with any combination of Remifentanil, Fentanyl, Alfentanil, or Sufentanil.
Users can add drugs and PK/PD model parameters to the system in addition to those included above.
Real-Time Case Capture: Drug entry system facilitates recording drugs administered real-time or retrospectively from intra-operative record. Save to Case Library for later review.
Case Library: Save actual cases or design and add your own cases to the library to record and demonstrate dosing strategies for a variety of patient types and drugs.
AnestAssist runs an enhanced user interface full screen natively on the iPad and in standard mode on the iPhone/iPod. The core functionality is the same on both.
Please see www.palmahealthcare.com for detailed information.
For Educational Use Only
Anesthesiologists, CRNA’s, veterinarians, and other clinicians involved with anesthesiology, from residents to the very experienced, will find AnestAssist a valuable tool for understanding rational dosing strategies tailored to individual patients.
Mathematical models, published in peer reviewed anesthesia journals (see www.palmamhealthcare.com), which take into account patient weight, age, and gender, are used to estimate and chart:
Plasma Concentration (IV drugs)
Alveolar Concentration (Inhaled agents)
Effect Site Concentration
Probability of Effect (individual and combined drug interactions)
Analgesia: No response to laryngoscopy
Sedation: OAA/S < 2
NMB: T1/T0=50%
IV drugs included: Propofol, Remifentanil, Fentanyl, Alfentanil, Sufentanil, Dexmedetomidine, Ketamine, Lidocaine, Morphine, Midazolam, Atracurium, Cisatracurium, Rocuronium, and Vecuronium.
Inhaled agents included: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, and Nitrous Oxide.
Interactions modeled: Propofol, Sevoflurane, or Isoflurane with any combination of Remifentanil, Fentanyl, Alfentanil, or Sufentanil.
Users can add drugs and PK/PD model parameters to the system in addition to those included above.
Real-Time Case Capture: Drug entry system facilitates recording drugs administered real-time or retrospectively from intra-operative record. Save to Case Library for later review.
Case Library: Save actual cases or design and add your own cases to the library to record and demonstrate dosing strategies for a variety of patient types and drugs.
AnestAssist runs an enhanced user interface full screen natively on the iPad and in standard mode on the iPhone/iPod. The core functionality is the same on both.
Please see www.palmahealthcare.com for detailed information.
For Educational Use Only
Version history
1.9
2014-11-25
This app has been updated by Apple to display the Apple Watch app icon.
Fixed incompatibilities with iOS 8 which caused the app to freeze. Updated the user interface to iOS 7/8 look and feel.
Fixed incompatibilities with iOS 8 which caused the app to freeze. Updated the user interface to iOS 7/8 look and feel.
1.8
2010-12-08
User's can now enter custom PK/PD models for pediatric and veterinary use (in addition to adult specific models).
1.7.1
2010-10-11
Maintenance release - bug fix.
1.7
2010-09-23
- Users can now add additional drugs and custom PK/PD model parameters to the system
- Added PK/PD models for Atracurium, Cisatracurium, Rocuronium, and Vecuronium
- Added PK/PD models for Atracurium, Cisatracurium, Rocuronium, and Vecuronium
1.6
2010-05-28
- User definable reference concentration lines
- Case time base can be either "simulated" or "clock/real-time"
- At startup the previous session's view is restored (i.e. you see what you were viewing when the app was last exited.
- Case time base can be either "simulated" or "clock/real-time"
- At startup the previous session's view is restored (i.e. you see what you were viewing when the app was last exited.
1.5
2010-04-10
- iPad specific user interface
o AnestAssist PK/PD 1.5 will run on both the iPod/iPhone and the new iPad (i.e. it is a "Universal App"). The iPad U/I is much more efficient (fewer screens), but functionality and features are the same for all devices.
- Drug Given Graphs
o Added "drug given" graphs showing timing and amounts of infusions and boluses.
- Tap to display PK values
o Tapping a point in the PK graph displays a cursor and numerical readout of the PK concentrations at that time.
- PK Graph Display
o Patient gender, weight, height, and age displayed.
o Larger/bolder font used to increase readability.
- Workflow and Configurability
o After completing entry or edit of a drug given, the PK graph screen for the drug is immediately displayed.
o Default bolus and infusion units for each drug can now be selected in Settings.
o Units and graph limit/increment parameters for bolus given and infusion given graphs for each drug can be defined in Settings.
o The "secondary" graph on the PK screen can be selected in Settings to default to either Interations/Effects or Drug Given.
o AnestAssist PK/PD 1.5 will run on both the iPod/iPhone and the new iPad (i.e. it is a "Universal App"). The iPad U/I is much more efficient (fewer screens), but functionality and features are the same for all devices.
- Drug Given Graphs
o Added "drug given" graphs showing timing and amounts of infusions and boluses.
- Tap to display PK values
o Tapping a point in the PK graph displays a cursor and numerical readout of the PK concentrations at that time.
- PK Graph Display
o Patient gender, weight, height, and age displayed.
o Larger/bolder font used to increase readability.
- Workflow and Configurability
o After completing entry or edit of a drug given, the PK graph screen for the drug is immediately displayed.
o Default bolus and infusion units for each drug can now be selected in Settings.
o Units and graph limit/increment parameters for bolus given and infusion given graphs for each drug can be defined in Settings.
o The "secondary" graph on the PK screen can be selected in Settings to default to either Interations/Effects or Drug Given.
1.4
2010-03-08
New drugs: dexmedetomidine, ketamine, lidocaine, morphine, and midazolam.
New models: additional/alternative models added for many supported drugs. Most (but not all) drugs now have at least one model using patient covariates.
Isoflurane-opioid interaction effects model added.
Many workflow/user interface improvements to speed drug entry and viewing.
Additional units: mg/hr, mg/min, mcg/hr, mcg/min, mg/kg/hr
Additional configuration options and model selections for all drugs.
Model reference and patient covariate information for all drugs displayed.
Graph time scale improvements.
Bug fixes.
New models: additional/alternative models added for many supported drugs. Most (but not all) drugs now have at least one model using patient covariates.
Isoflurane-opioid interaction effects model added.
Many workflow/user interface improvements to speed drug entry and viewing.
Additional units: mg/hr, mg/min, mcg/hr, mcg/min, mg/kg/hr
Additional configuration options and model selections for all drugs.
Model reference and patient covariate information for all drugs displayed.
Graph time scale improvements.
Bug fixes.
1.3.1
2010-02-02
Inhaled modeling expanded and enhanced.
- Agents supported: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, Nitrous Oxide
- User control of vaporizer settings (%) and fresh gas flow (FGF)
- Calculates and displays inspired (circuit) concentration, alveolar concentration, brain tissue concentration
PK graphs can now be viewed in horizontal (landscape) orientation.
Many user interface improvements.
Bug fix for time round-off error in version 1.3
- Agents supported: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, Nitrous Oxide
- User control of vaporizer settings (%) and fresh gas flow (FGF)
- Calculates and displays inspired (circuit) concentration, alveolar concentration, brain tissue concentration
PK graphs can now be viewed in horizontal (landscape) orientation.
Many user interface improvements.
Bug fix for time round-off error in version 1.3
1.3
2010-01-20
Inhaled modeling expanded and enhanced.
- Agents supported: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, Nitrous Oxide
- User control of vaporizer settings (%) and fresh gas flow (FGF)
- Calculates and displays inspired (circuit) concentration, alveolar concentration, brain tissue concentration
PK graphs can now be viewed in horizontal (landscape) orientation.
Many user interface improvements.
- Agents supported: Sevoflurane, Isoflurane, Desflurane, Enflurane, Halothane, Nitrous Oxide
- User control of vaporizer settings (%) and fresh gas flow (FGF)
- Calculates and displays inspired (circuit) concentration, alveolar concentration, brain tissue concentration
PK graphs can now be viewed in horizontal (landscape) orientation.
Many user interface improvements.
1.2
2009-12-22
- PK graph concentration axis fixed scale (upper limit and tic mark increment) for each drug can be set in Settings
- Drug Given List entries can now be changed/edited by tapping them.
- Default concentration for all drugs can be set in Settings
- Drug Given List entries can now be changed/edited by tapping them.
- Default concentration for all drugs can be set in Settings
1.1.1
2009-12-08
Correction to Sevoflurane PK model
1.1
2009-11-21
Added inhaled agent modeling (Sevoflurane). Drug entry process improved, more unit types supported. Graphs show clock time, vertical axis auto-scales.
1.0
2009-08-05
Ways to hack AnestAssist PK/PD
- Redeem codes (Get the Redeem codes)
Download hacked APK
Download AnestAssist PK/PD MOD APK
Request a Hack
Ratings
5 out of 5
1 Ratings
Reviews
etherDad,
Great app - I use it in the OR regularly
I've been using this for almost a year, and it is fantastic. I teach residents and I use this to show the difference that solubility coefficients make in short vs long cases, how WHEN you give fentanyl has a profound effect on plasma level and Ce, how to plan sufentanil infusions, TIVA, neuromuscular blockade. Very easy to use, and now I have a library of real cases and simulated cases to review with my residents.
Ozcan,
I just used it-again!
I had this app since it was newly released, and have used it almost daily since then. I just modeled cisatracurium infusion and glanced at the PK/PD (T1 50%) to help with our understanding of the dosing. Then, with my resident, we plotted the sevoflurane/fentanyl and looked at the interaction model by Manyam. If you are administering anesthesia, buy it! If you are using TIVA as your technique, you should have bought it when it came out!
Mfiedler,
Not worth the price. Think twice.
Idea is great. Data entry is cumbersome. Time hard to track; you must enter in clock hours but is displayed from time 0. Graphs truncate at seemingly random times from time zero, even if curve has not decayed to baseline. Graph scale doesn't change if you use larger doses than the software designer anticipated (as many may do with fentanyl, for example.) It doesn't take long to regret making the purchase price.
.AnesMD,
Poor execution
It should have been a red flag that this app has not been updated since 2010.
ClinicalPK,
Good PK SImulator, Solid Support
In the past I have used several very good PC based PK simulators, TIVA-Trainer and GasMan, both of which cost well over $100 each. This application compares very favorably in terms of functionality, but at a fraction of the cost, and it's practical to bring this on my iPod into the OR for teaching and review purposes.
The user interface is pretty good and I didn't have too many problems figuring out how to use it. Actually the data entry and display is quite clever considering that with the small screen (compared to a PC) some operations need to be spread out over several screens. I expect the iPad version is better in this respect.
The app comes with PK/PD models for quite a few IV and volatile agents, and also allows you to add additional drugs and PK models if you wish (but beware, adding models is a bit complex and only for knowledgeable users). Many aspects of the PK display are configurable, including scaling of the concentration axis and a choice of "real-time" time axis and drug entry (to record an actual case as opposed to experimenting with the simulator). I found this especially useful for teaching purposes in the OR. Also there is the ability to set "reference concentration" lines for drugs for students to use to visualize target concentrations.
Questions to the developer were answered almost immediately, and he seems sincerely interested in feedback and suggestions.
My own suggestion to the developer is to add some way for me to export "cases" to my PC. I'd like to be able to add them to a presentation, or forward as examples to students. As a side note, the idea of 'cases' is this app is not as useful as it could be. This is one area that could use more work, for example to be able to search and sort. Kind of cumbersome now beyond a few cases.
There's a lot more to this app than I have time to write about. It's certainly worth having a look at, especially at the bargain price.
The user interface is pretty good and I didn't have too many problems figuring out how to use it. Actually the data entry and display is quite clever considering that with the small screen (compared to a PC) some operations need to be spread out over several screens. I expect the iPad version is better in this respect.
The app comes with PK/PD models for quite a few IV and volatile agents, and also allows you to add additional drugs and PK models if you wish (but beware, adding models is a bit complex and only for knowledgeable users). Many aspects of the PK display are configurable, including scaling of the concentration axis and a choice of "real-time" time axis and drug entry (to record an actual case as opposed to experimenting with the simulator). I found this especially useful for teaching purposes in the OR. Also there is the ability to set "reference concentration" lines for drugs for students to use to visualize target concentrations.
Questions to the developer were answered almost immediately, and he seems sincerely interested in feedback and suggestions.
My own suggestion to the developer is to add some way for me to export "cases" to my PC. I'd like to be able to add them to a presentation, or forward as examples to students. As a side note, the idea of 'cases' is this app is not as useful as it could be. This is one area that could use more work, for example to be able to search and sort. Kind of cumbersome now beyond a few cases.
There's a lot more to this app than I have time to write about. It's certainly worth having a look at, especially at the bargain price.
church of reason,
Use it daily
After practicing anesthesia for 17 years I learned a lot about how various infusion rates and boluses will effect my anesthetic by using this software. For a US based anesthesiologist who does not have access to target controlled infusion pumps this is the best option to calculate plasma levels that I am aware of. As a Mac user I could never get StanPump to work and this comes at a fraction of a cost of the TIVA trainer from Eurosiva.org with an interface that is way more user friendly. AnestAssist uses the same published algorithms as TCI's and the other programs. I have used it for a year or more on iPhone and iPad and the only rare glitch I have seen was the program quitting suddenly but I was able to resume where I left off by opening up the application again. To be able to interpret the data properly you will have to know what plasma or effect site concentrations you are aiming for and we think in terms of doses and know little about plasma concentrations. For starters try to simulate various regimens to achieve a propofol plasma concentration of 3 or 4 mcg/ml (common target for TCI's) then set the infusion to 0 mcg/kg/min and see how soon will plasma concentrations reach 1-1.4 mcg/ml where most patients will wake up. Try infusion rate changes versus boluses and look at how long it takes for plasma concentrations to change. Then do the same for dexmedetomidine. You will be surprised at what you learn.
In summary: excellent, easy to use tool you just have to learn what to do with the results.
In summary: excellent, easy to use tool you just have to learn what to do with the results.
