I use X-Plane 11 & FSX Deluxe (DVD) on Win-10. My MacBook Pro isn’t my most powerful so I haven’t tried that, but have high confidence that it would work. Do not try to multi-task while setting it up, it’s easy, but you have to do it right. Easiest install was FSX, get the add-on installed, try RF Lite to test, then go for it. X-Plane runs as a plug-in and that’s obviously separate from what FSX uses. Run X-Plane after the install, it’ll create an ini file, and there will be a no-connect error at first, then you’ll edit it for your IP address. The interface is nice and smooth. Even on WiFi, it’s almost perfectly synced with the sim. Makes it nice to view parts of virtual cockpit and still be able to see that I’m maintaining altitude and airspeed. Some pay ware like my Airbus’s on X-Plane aren’t really going to need this, it’s mostly just a repeater of the instruments. But for built-in airplanes, or less avionics-friendly payware planes, (like a fighter) it’s nice to have this interface, which will give you some standardization and one-finger operability. Will probably get the bundle pack for my iPhone to give me one more screen for radios and autopilot.